• Voluminous literature about the neuroendocrine mechanism of

  2023-09-20

  

  Voluminous literature about the neuroendocrine mechanism of reproduction and energy regulation has emerged from studies involving mammalian species. The avian infundibular nucleus (equivalent structure to the mammalian arcuate nucleus) consists of two neuronal populations, one of which expresses neu

• br Conclusions Triptans are HT B D

  2023-09-20

  

  Conclusions Triptans are 5-HT1B/1D/(1F) receptors agonists and are considered as the gold standard for acute migraine treatment that have been proven effective. Unfortunately, they are contraindicated in patients with cardiovascular diseases due to their vasoconstrictor (side) effects (MaassenVan

• Extracellular adenosine acts as a local modulator

  2023-09-20

  

  Extracellular adenosine acts as a local modulator of cell function via four adenosine receptor subtypes (A1Rs A2AR, A2BR, and A3R) that are involved in numerous physiological and pathophysiological processes [31]. Each is encoded by a separate gene and has different functions, although with some ove

• AdK as an important upstream regulator of adenosine

  2023-09-20

  

  AdK as an important upstream regulator of adenosine-based homeostasis represents a promising drug target since it leads to an increase in adenosine concentrations. Taking into account that the adenosine formation is only increased in affected tissues under stress with high adenosine levels, AdK inhi

• br Occurrence of Inosine in RNA Inosine is widespread among

  2023-09-20

  

  Occurrence of Inosine in RNA Inosine is widespread among various types of RNAs including transfer RNA (tRNA), ribosomal RNA (rRNA), messenger RNA (mRNA), long noncoding RNA (lncRNA), and microRNA (miRNA). Within these RNAs, inosine can appear in different locations as well. Table 1 lists examples

• Several reports of single cases of MG patients treated

  2023-09-20

  

  Several reports of single cases of MG patients treated with Rituximab have claimed a favourable response (Baek et al., 2007, Gajra et al., 2004, Hain et al., 2006, Thakre et al., 2007, Wylam et al., 2003, Zaja et al., 2000). We report our experience with Rituximab in 6 patients with severe MG, 3 pa

• Until now there are no report regarding the relationship

  2023-09-20

  

  Until now, there are no report regarding the relationship of CD21 and MG. In the present study, we aimed to characterize the AchR specified Pentamidine dihydrochloride and investigated the role of CD21 in immunopathogenesis of MG. We utilized the Allophycocyanin (APC)-conjugated AchR to measure the

• br Conclusion There have been multiple clinical trials and

  2023-09-20

  

  Conclusion There have been multiple clinical trials and pre-clinical studies that have tested the utility of 5ARIs in treating prostate disease, as summarized in Fig. 1. Inhibiting androgen action through the use of finasteride and dutasteride has been established as a valuable resource for physi

• Matsuzaki et al attempted fertility therapy in a

  2023-09-20

  

  Matsuzaki et al. attempted fertility therapy in a 26-year-old female with secondary amenorrhea and 17OHD who was a 821 heterozygote for delF53/54 and the missense mutation H373L, which has a 6.1-mm endometrial stripe on cycle day 7, with a low serum E2 concentration of 36.5 pg/mL; no pregnancy resu

• microcystin lr br Autophagy at the Synapse The synapse is a

  2023-09-20

  

  Autophagy at the Synapse The synapse is a highly specialized neuronal compartment that forms the basic unit of communication between neurons. Communication relies on electrical signals that are propagated down the axon of the presynaptic neuron, where they trigger the quantal release of neurotran

• br The complementary role of chaperone

  2023-09-20

  

  The complementary role of chaperone mediated autophagy Chaperone-mediated autophagy (CMA) mediates the degradation of specific cellular proteins and participates in the regulation of lipid metabolism, DNA repair, or the response to stress (Kaushik and Cuervo, 2018). CMA provides an alternative pa

• To introduce in a simple way the variability

  2023-09-20

  

  To introduce in a simple way the variability in the concentration of the proteins involved in the process, and to consider possible stochastic effects due to possible finite sizes of the populations involved in the problem, the dynamics of each cell is studied using the Gillespie’s algorithm (Gilles

• Serum concentrations of acute phase proteins APP and of

  2023-09-20

  

  Serum concentrations of acute phase proteins (APP) and of antioxidants have proved to be clinically useful biomarkers of pyometra in different species, including bitches, cows and mares [[11], [12], [13], [14], [15]]. Acute phase proteins are being increasingly used in both human and veterinary medi

• Using this cheese mimicking matrix we

  2023-09-20

  

  Using this cheese-mimicking matrix, we screened the antifungal activity of 44 LAB fermented milk-based products and 23 LAB isolates used as protective cultures against 4 fungal targets. The LAB were obtained from the culture collections of CIRM-BIA (Centre International de Ressources Microbienne-Bac

• On the contrary Birrel and colleagues observed divergent pro

  2023-09-19

  

  On the contrary, Birrel and colleagues observed divergent proliferative responses to androgens in different BC cell lines: DHT and mibolerone were found to inhibit the T47-D and ZR-75-1 PPY A synthesis growth, while the proliferation of MCF-7 cells was increased by both the androgens [53]. It is wo

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