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br Acknowledgments This research was supported
2022-05-26

Acknowledgments This research was supported by a grant from the Korea Health Technology R&D Project through the Korean Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI17C0616). Dr. Jun-Mo Yang was supported by the Natio
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The genes for the receptors for peptides similar
2022-05-26

The genes for the receptors for peptides similar to glucagon are dispersed on three human chromosomes, with two on chromosome 17 (GCGR and GLP2R) and one each on chromosomes 6 (GLP1R) and 19 (GIPR) (see Table S1). The exon–intron gene structures of these genes are similar, as are the genes for other
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Phosphatase Inhibitor Cocktail (2 Tubes, 100X) The eradicati
2022-05-26

The eradication of agonist activity in compound was also confirmed in the ex vivo growth hormone (GH) release experiment conducted in isolated primary rat pituitary Phosphatase Inhibitor Cocktail (2 Tubes, 100X) as shown in . Compound did not produce any noticeable GH secretion at up to 10μM conc
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br Central control of GI
2022-05-26

Central control of GI ghrelin secretion The CNS communicates with the GI tract through the vagus nerve originating in the DMV and sympathetic spinal afferents emanating from the thoracic spinal chord (Bray, 2000). The cells that secrete peripheral ghrelin are under direct control of these two pat
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br Acknowledgements br Introduction This article similar to
2022-05-26

Acknowledgements Introduction This article, similar to those before [1,2], presents a selection of nails for those red blood cell physiologists with hammers. The various topics are not necessarily lost for, like occupants on a carousel, they reappear periodically. Sometimes, however, some arti
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br Presenilins in protein trafficking proteolysis and
2022-05-26

Presenilins in protein trafficking, proteolysis and degradation An obvious explanation for the role of presenilins and γ-secretase in protein trafficking and degradation is that many reported γ-secretase substrates are functionally involved in protein transport. For example, members of the mammal
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The overall decrease in consummatory drive
2022-05-26

The overall decrease in consummatory drive seen in rodents treated with naltrexone in previous studies is in accordance with the effects seen with mice treated with SNAP 37889 in this study. While it may seem inappropriate to use a broad-acting drug like SNAP 37889 that suppresses overall consummato
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Introduction Since the development of
2022-05-26

Introduction Since the development of the first radioimmunoassay (RIA) to measure hormone levels in the late 1950s, for which Rosalyn Sussman Yalow was awarded the Nobel Prize for Medicine in 1977 (the second woman ever receiving it), the use of cftr in molecular research has increased tremendousl
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The GH family has potential applications in various industri
2022-05-26

The GH family has potential applications in various industries. A putative ORF encoding α-galactosidase, namely GalR, with a low identical match and e-value and high query coverage in the metagenome was selected because it demonstrated considerable activity. GalR shared 65% identity with the GH 27 p
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Analysis of the i motif structures
2022-05-26

Analysis of the i-motif structures during biased unfolding of G-quadruplexes leads to the conclusion that at acidic pH the i-motif is absolutely unaffected by that process. The hydrogen bonds within the i-motif are intact (Fig. 3D) and they only fluctuate around mean values. On the other hand, the i
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herpes simplex virus 1 Prior models suggest that the termina
2022-05-26

Prior models suggest that the terminal ends of the endocrine FGFs individually determine FGFR and KLB recognition, with little or no cross-talk. Our results confirm that short C-terminal sequences are necessary and sufficient to bind KLB and, supportive of a common mechanism, the underlying structur
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Interestingly the subcellular localization of FBPase in
2022-05-26

Interestingly, the subcellular localization of FBPase in hepatocytes and proximal tubule chk1 inhibitor reveals that FBPase is also able to translocate to the nucleus in these cell types. The nuclear localization of muscle-FBPase was recently reported [35]. This data corroborate our results on the a
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Introduction RNA splicing occurs in the nucleus when noncodi
2022-05-26

Introduction RNA splicing occurs in the nucleus when noncoding sequences (introns) are removed from the pre-mRNA transcript and coding sequences (exons) are joined to form a mature mRNA [1,2]. This reaction is catalyzed by a multiprotein complex called spliceosome. The spliceosome consists of five
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A previous study from our
2022-05-26

A previous study from our institution showed moderate correlation between the APTT and Anti-FXa assays, prompting an institution-wide change to an Anti-FXa based monitoring of unfractionated heparin. The current study is a descriptive analysis to evaluate the clinical outcomes in this pediatric coho
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Oxaliplatin br Effects of norepinephrine on HIV
2022-05-26

Effects of norepinephrine on HIV infection The few in vitro studies specifically examining the effects of norepinephrine on HIV infection suggest that this catecholamine can influence the HIV replication process, although the precise mechanism is unclear. Cole and colleagues found concentrations
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